Description
Thorne Research 5-MTHF 1 mg (60 vcaps)
Folate – an essential B vitamin in its active, tissue-ready form
- a breakthrough in folate supplementation
- formulated for optimum absorption*
- provides an excellent source of folate for pregnant women*
- supports healthy heart and nerve function*
Folic acid must be converted to its active forms to be used by the body.* This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the bodys needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.*
Because deficiencies of folic acid have been linked to low-birth-weight infants and neural tube defects, folic acid requirements double during pregnancy.* The Centers for Disease Control and Prevention recommends folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant.* Supplementation with the more active form may be preferable.*
In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine.* Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.*
It is important for women of childbearing age to get enough folic acid – not just those who are planning to become pregnant.* Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day – especially before conception and during early pregnancy.*
Thorne Research 5-MTHF 1 mg (60 vcaps)
叶酸 – 其活性的，组织形式的必需的B族维生素
- 叶酸补充剂的突破
- 制定最佳吸收*
- 为孕妇提供叶酸的优良来源*
- 支持健康心脏和神经功能*
叶酸必须转化为其活性形式供身体使用。*这是在肠和肝中发生的多步生化过程。在肠或肝功能障碍的存在下，这种转化可能不足以发生以满足身体的需要。此外，高达60％的美国人群可能具有遗传性酶缺陷，使得它们难以将叶酸转化为活性5-MTHF。对于这些个体和许多其他人，5-MTHF补充可能是更有效的叶酸补充的方法。
因为叶酸的缺乏与低出生体重的婴儿和神经管缺陷有关，叶酸需要在怀孕期间需要两倍。*疾病控制和预防中心建议对所有育龄妇女补充叶酸，因为最大的需要是在孕早期，当一个女人甚至可能不知道她怀孕*补充更积极的形式可能是更可取的。
与维生素B12一致，5-MTHF作为甲基供体参与氨基酸同型半胱氨酸向甲硫氨酸的转化。*甲基供体对许多生化转化过程至关重要，包括5-羟色胺，褪黑激素和脱氧核糖核酸。*
育龄期的妇女获得足够的叶酸是非常重要的，而不仅仅是计划怀孕的那些人。*只有50％的怀孕是计划的，所以任何怀孕的妇女每天应该获得足够的叶酸 – 特别是以前概念和早期怀孕期间。
Serving Size: 1 Capsule
Amount Per Serving
Folate … 1mg
(as L-5-Methyltetrahydrofolate*)
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
*This product uses Gnosis S.p.A.s L-5-Methyltetrahydrofolate (Extrafolate-S®). Extrafolate-S is a registered trademark of Gnosis S.p.A.
每集装箱份量：60
每天服用1〜3次，或按保健医生的建议服用。
份量：1胶囊
每份的量
叶酸 … 1mg
（作为L-5-甲基四氢叶酸*）
其他成分：微晶纤维素，羟丙甲纤维素（来自纤维素）胶囊，亮氨酸，二氧化硅。
*本产品使用Gnosis S.p.A.s L-5-甲基四氢叶酸（Extrafolate-S®）。 Extrafolate-S是Gnosis S.p.A.的注册商标。
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.
INTERACTIONS
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexates anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
过敏警告
本产品禁忌在对任何其成分具有超敏反应史的个体中。
怀孕警告
如果怀孕，请在使用本产品前咨询您的保健医生。
互动
不推荐与甲氨蝶呤癌症治疗同时使用5-甲基四氢叶酸（5-MTHF）补充剂，因为它可以干扰甲氨蝶呤抗肿瘤活性; 然而，该叶酸来源未显示干扰甲氨蝶呤的抗炎活性。 服用甲氨蝶呤治疗牛皮癣或类风湿性关节炎的个体可以安全服用含有叶酸的补充剂。
